The main purpose of this study is to investigate the relationship between attitude towards mathematics and academic performance in mathematics among female students in Bandar Abbas.The research method used in this study is descriptive, correlational, and applied in terms of purpose. The statistical population in this study includes all 2576 female students in Bandar Abbas. The sample size was determined using the Morgan table and 344 were selected as a statistical sample using simple random sampling. The research tools in this study include the Aiken Standard Questionnaire on Attitude to Mathematics (2001) and the Pham and Taylor Standard Questionnaire on Academic Performance (2002). The basis for scoring is The validity of the questionnaires was assessed based on the experts' views and its reliability was also assessed based on the Cronbach's alpha test and was evaluated and calculated as (0.820) and (0.920), respectively, which indicates the desired reliability of the research questionnaire. In this study, Pearson's correlation coefficient and multiple regression analysis were used to analyze the research hypotheses. The results of this study showed that there is a positive and significant relationship between the attitude towards mathematics and academic performance in the mathematics lesson of female students in the first high school; also, there is a positive and significant relationship between the enjoyment of mathematics and academic performance in the mathematics lesson of female students in the first high school; there is a negative and significant relationship between the fear of mathematics and academic performance in the mathematics lesson of female students in the first high school; there is a positive and significant relationship between the value and importance of mathematics and academic performance in the mathematics lesson of female students in the first high school. Students' performance in mathematics is largely dependent on their attitude towards this subject. Consequently, by changing attitudes in a positive direction, students' mathematical performance can be improved.